Information about Fluner 10 Tablet

"Fluner 10" appears to refer to a medication containing Flunarizine, typically at a dosage of 10 mg. Flunarizine is a calcium channel blocker primarily used in the treatment of certain medical conditions. Here’s an overview of its uses, mechanism, and precautions:

Flunarizine (10 mg)

1. Migraine Prophylaxis:

   • Flunarizine is commonly prescribed to prevent migraines. It helps reduce the frequency and severity of migraine attacks by modulating the flow of calcium in the brain and reducing the hyperexcitability of neurons that can trigger migraines.

2. Vertigo:

   • It is also used in the treatment of vestibular disorders, including vertigo. By stabilizing the vestibular system, Flunarizine can help manage dizziness and balance issues.

3. Other Neurological Disorders:

   • Occasionally, Flunarizine may be used off-label for other conditions, such as epilepsy (as an adjunctive treatment) or other types of headaches.

Mechanism of Action

Flunarizine is a selective calcium entry blocker. It works by inhibiting the entry of calcium into cells, which is crucial in the transmission of nerve impulses and muscle contraction. By reducing calcium influx, Flunarizine helps stabilize neuronal activity, thereby preventing excessive nerve firing associated with migraines and other conditions.

Dosage and Administration

• Typical Dosage: The usual adult dosage is 10 mg once daily at bedtime. However, the dose can vary based on the specific condition being treated and the patient’s response to the medication.
• Administration: It is generally recommended to take Flunarizine at night, as it can cause drowsiness. The medication can be taken with or without food.

Precautions and Side Effects

• Common Side Effects: Drowsiness, weight gain, dry mouth, and gastrointestinal disturbances are common. Drowsiness is particularly notable, so caution should be taken when engaging in activities requiring alertness, such as driving.
• Serious Side Effects: Long-term use can lead to depression or extrapyramidal symptoms (movement disorders similar to those seen in Parkinson's disease). It is important to monitor for these symptoms, especially in elderly patients.
• Contraindications: Patients with a history of depressive disorders, Parkinson’s disease, or extrapyramidal disorders should avoid using Flunarizine. Additionally, it should not be used in individuals with known hypersensitivity to the drug.

Conclusion

Flunarizine is an effective medication for preventing migraines and managing vertigo. As with any medication, it is essential to use it under the guidance of a healthcare professional to monitor for potential side effects and adjust the dosage as necessary. If you have any specific concerns or conditions, consult your healthcare provider for personalized advice.