Information about Nexpro L Capsule

Nexpro L Capsule ER is a combination medication that contains Esomeprazole and Levosulpiride. It’s commonly prescribed to treat acid-related conditions associated with gastroesophageal reflux disease (GERD) and functional dyspepsia (indigestion), especially when accompanied by symptoms like nausea, bloating, and delayed gastric emptying.

• Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, providing relief from heartburn, acid reflux, and related conditions.
• Levosulpiride is a prokinetic agent that improves gastrointestinal motility, helping food pass more quickly through the stomach and reducing symptoms like nausea and bloating.

Uses:

Nexpro L Capsule ER is prescribed for:

1. Gastroesophageal Reflux Disease (GERD) with symptoms like heartburn, regurgitation, and acid reflux.
2. Functional Dyspepsia (Indigestion) with symptoms of bloating, nausea, and delayed gastric emptying.
3. Acid Peptic Disorders: Where both acid reduction and improved motility are beneficial.

Dosage and Administration:

• Typical Dosage: One capsule per day, usually taken before a meal, as directed by your doctor.
• Administration: Swallow the capsule whole with a glass of water. Do not crush or chew it, as it is an extended-release (ER) formulation.

Side Effects:

Common side effects of Nexpro L Capsule ER include:

• Headache
• Dizziness
• Nausea
• Abdominal Pain
• Constipation or Diarrhea

Rarely, it may cause drowsiness, fatigue, or, in some cases, mild hormonal effects. Seek medical attention if you experience severe symptoms.

Precautions:

• Allergies: Avoid if you have known allergies to Esomeprazole, Levosulpiride, or similar medications.
• Long-Term Use: Prolonged use of PPIs can increase the risk of vitamin B12 deficiency, magnesium deficiency, and bone fractures.
• Kidney and Liver Issues: Use with caution if you have impaired kidney or liver function, as dose adjustments may be necessary.
• Pregnancy and Breastfeeding: Consult a healthcare provider before use, as safety during pregnancy and breastfeeding is not fully established.

Drug Interactions:

• Antifungals and Antiretrovirals: Esomeprazole may reduce the effectiveness of drugs like Ketoconazole and Atazanavir.
• Antipsychotics: Levosulpiride may interact with certain antipsychotic medications.
• Blood Thinners (e.g., Warfarin): Esomeprazole may affect blood clotting, requiring monitoring.

Storage:

• Store at room temperature, away from direct sunlight and moisture.
• Keep out of reach of children.

Summary:

Nexpro L Capsule ER combines acid suppression with improved stomach motility, making it effective for GERD and dyspepsia, especially with accompanying nausea and bloating. Follow the dosage carefully and avoid long-term use without medical advice due to potential deficiencies and other risks.