Information about Gemer DS 1 Tablet

Gemer DS 1 Tablet PR is an oral antidiabetic medication used to manage type 2 diabetes. The "DS" typically stands for "Double Strength," and "PR" indicates that it is a "Prolonged Release" or "Extended Release" formulation. This tablet generally contains the following active ingredients:

1. Glimepiride (1 mg): A sulfonylurea that stimulates the pancreas to release more insulin, which helps lower blood sugar levels.
2. Metformin (500 mg or 1000 mg in some formulations): A biguanide that decreases glucose production in the liver, increases insulin sensitivity, and helps the body use insulin more effectively.

Uses:

• Type 2 Diabetes Management: Gemer DS 1 Tablet PR is used to control blood sugar levels in patients with type 2 diabetes, especially when diet and exercise alone are not sufficient.
• Combination Therapy: This combination of Glimepiride and Metformin is used when monotherapy with either drug does not adequately control blood sugar levels.

How It Works:

• Glimepiride: Stimulates the release of insulin from the pancreatic beta cells, thereby lowering blood sugar levels, particularly after meals.
• Metformin: Reduces glucose production in the liver, delays glucose absorption from the intestines, and improves insulin sensitivity, leading to better glucose utilization by muscles and fat tissues.

Dosage:

• Prolonged Release (PR): This formulation is designed to release the medication slowly over time, allowing for once-daily dosing and maintaining steady blood sugar levels throughout the day.
• It is typically taken once daily with a meal, usually breakfast or the first main meal, to reduce the risk of hypoglycemia (low blood sugar).

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, abdominal pain, dizziness, and headache.
• Hypoglycemia: The combination can cause low blood sugar, especially if meals are skipped, or if there is excessive physical activity without proper nutritional intake.
• Gastrointestinal Issues: Metformin can cause gastrointestinal discomfort, particularly when starting treatment. These symptoms usually subside as the body adjusts to the medication.
• Weight Gain: Glimepiride may cause slight weight gain in some patients.
• Lactic Acidosis: Though rare, Metformin can cause a serious condition called lactic acidosis, especially in patients with kidney issues, liver disease, or severe dehydration.

Precautions:

• Kidney and Liver Function: Regular monitoring of kidney and liver function is essential, as Metformin is contraindicated in patients with severe kidney impairment and can affect liver function.
• Heart Conditions: Patients with heart disease should use this medication cautiously, as there is a potential risk of heart-related side effects.
• Alcohol Consumption: Alcohol should be minimized or avoided, as it can increase the risk of lactic acidosis with Metformin and hypoglycemia with Glimepiride.
• Surgery and Stress: During periods of stress, such as surgery or infection, a doctor may temporarily switch you to insulin to better control blood sugar levels.

Lifestyle Considerations:

• Diet: A balanced diet with controlled carbohydrate intake is crucial for managing diabetes while on Gemer DS 1.
• Exercise: Regular physical activity is recommended to improve insulin sensitivity and enhance the effectiveness of the medication.
• Regular Monitoring: Blood sugar levels should be regularly monitored to ensure the medication is working effectively.