Information about OFM Suspension

OFM 50/100 Suspension is a combination medication commonly prescribed to treat bacterial infections, particularly in children. It contains two active ingredients:

1. Ornidazole (50 mg): An antibiotic that belongs to the nitroimidazole class and is effective against anaerobic bacteria and certain parasites. It works by inhibiting the DNA synthesis of bacteria, preventing their growth.
2. Ofloxacin (100 mg): A fluoroquinolone antibiotic effective against various bacterial infections. It works by inhibiting bacterial enzymes necessary for DNA replication, leading to the death of bacteria.

Uses:

OFM 50/100 Suspension is generally prescribed for:

• Bacterial Infections in the Gastrointestinal Tract: Effective for infections like diarrhea, dysentery, and gastroenteritis.
• Respiratory and Urinary Tract Infections: May be used to treat infections in the respiratory tract or urinary system if caused by susceptible bacteria.
• Other Bacterial Infections: Skin infections and infections of other soft tissues.

Dosage and Administration:

• Typical Dosage: Dosage depends on the child's age, weight, and the severity of the infection. A healthcare provider will specify the exact dose and frequency.
• Administration: The suspension should be taken orally, and it’s usually advised to shake well before each dose to ensure even distribution of the medication. It can be taken with or without food, but taking it with food may help reduce stomach upset.

Side Effects:

Common side effects may include:

• Nausea and Vomiting
• Diarrhea or Stomach Pain
• Dizziness or Headache
• Loss of Appetite

Serious Side Effects:

While rare, serious side effects can include:

• Allergic Reactions: Symptoms such as rash, itching, or swelling of the face, tongue, or throat require immediate medical attention.
• Tendonitis or Tendon Rupture: Ofloxacin has been associated with an increased risk of tendon rupture, particularly in those with existing tendon problems.
• Severe Diarrhea: Persistent diarrhea may be a sign of a new infection (antibiotic-associated colitis).
• Neurological Effects: Seizures or confusion may occur, especially in those with a history of epilepsy or neurological conditions.

Precautions:

• Allergy: Do not use this medication if your child is allergic to any of its ingredients or to other similar antibiotics.
• Kidney or Liver Impairment: Dose adjustments may be required in children with kidney or liver issues.
• Avoid Sun Exposure: Ofloxacin can make the skin more sensitive to sunlight, so sun exposure should be limited during treatment.

Drug Interactions:

• Antacids or Supplements: Calcium, magnesium, or iron supplements can reduce the absorption of Ofloxacin, so it’s best to avoid giving these together.
• Blood Thinners: May interact with blood-thinning medications, increasing bleeding risk.
• Other Antibiotics: Combining with certain antibiotics may increase the risk of side effects.

Storage:

Store the suspension in a cool, dry place away from direct sunlight. Follow storage instructions on the package, and do not use beyond the expiration date. Keep out of reach of children.

Summary:

OFM 50/100 Suspension is a combination of Ornidazole and Ofloxacin, primarily prescribed to treat bacterial and certain parasitic infections in children. It is effective for gastrointestinal, respiratory, and urinary tract infections, among others. Make sure to follow the prescribed dosage, monitor for any side effects, and keep your healthcare provider informed of any other medications the child is taking.