Information about Nexpro IT Capsule

Nexpro IT Capsule SR is a combination medication containing Esomeprazole and Itopride. It is commonly used to manage acid reflux and other gastrointestinal issues that involve delayed stomach emptying and indigestion.

• Esomeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid, helping relieve acid-related symptoms like heartburn and acid reflux.
• Itopride is a prokinetic agent that enhances gastrointestinal motility, allowing food to pass more quickly through the stomach, which helps relieve symptoms like bloating, nausea, and fullness.

Uses:

Nexpro IT Capsule SR is prescribed for:

1. Gastroesophageal Reflux Disease (GERD): Treats symptoms of acid reflux and heartburn.
2. Functional Dyspepsia: Helps in cases of indigestion and bloating, often caused by slow gastric emptying.
3. Acid Peptic Disorders: Useful in conditions requiring acid reduction and improved motility.

Dosage and Administration:

• Typical Dosage: One capsule per day, usually taken 30 minutes before a meal, as prescribed by your healthcare provider.
• Administration: Swallow the capsule whole with water. Do not crush or chew it, as it is a sustained-release (SR) formulation.

Side Effects:

Common side effects of Nexpro IT Capsule SR include:

• Headache
• Nausea
• Dizziness
• Abdominal Pain
• Diarrhea or Constipation

In rare cases, more serious side effects, such as allergic reactions or hormonal effects from Itopride, may occur. Contact a healthcare provider if any severe or persistent side effects occur.

Precautions:

• Allergy: Avoid if you are allergic to Esomeprazole, Itopride, or other PPIs.
• Long-Term Use: Prolonged use may lead to vitamin B12 deficiency, magnesium deficiency, or an increased risk of bone fractures.
• Liver and Kidney Issues: Caution is advised for individuals with impaired liver or kidney function, as dose adjustments may be necessary.
• Pregnancy and Breastfeeding: Consult a healthcare provider before use if you are pregnant or breastfeeding.

Drug Interactions:

• Antiretroviral Medications: May reduce the effectiveness of drugs like Atazanavir.
• Antifungals: Reduced absorption with drugs like Ketoconazole.
• Blood Thinners (e.g., Warfarin): Esomeprazole may affect blood clotting, requiring monitoring.

Storage:

• Store at room temperature, away from sunlight and moisture.
• Keep out of reach of children.

Summary:

Nexpro IT Capsule SR is helpful for treating acid reflux and indigestion with bloating and nausea. It combines acid suppression with improved gastric motility, providing dual action for better symptom relief.